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My daughter, Ivy, recently joined a swim club. As a former competitive swimmer, it’s been a delight to witness. Every time I take her to practice, I feel a wave of nostalgia that reminds me of all the many years I spent in the pool and all the many teammates I collected along the way. It excites me to think that she, too, will have her own experiences and life lessons, just as swimming taught me. But something peculiar struck me as I watched her practice: 45 minutes of their one-hour training was spent on the basics. Kick drills. Pull drills. All the essentials about swimming that we don’t think very much about, the foundational techniques that make for a good swimmer. When I think about my time as a swimmer, I don’t remember that part very muchthe boring basics. Yet, like Ivy, I most certainly spent an exorbitant amount of time developing those fundamentals in the early stages of my swim tenure, the parts of swimming that I took for granted, i.e., the obvious stuff. The same applies when it comes to our organizations; far too often, we take the obvious parts about leading people for granted. With the growing complexities of shepherding modern organizations, we tend to forget about the basicsthe obvious stuff. {"blockType":"mv-promo-block","data":{"imageDesktopUrl":"https:\/\/images.fastcompany.com\/image\/upload\/f_webp,q_auto,c_fit\/wp-cms-2\/2026\/01\/studio_16-9.jpg","imageMobileUrl":"https:\/\/images.fastcompany.com\/image\/upload\/f_webp,q_auto,c_fit\/wp-cms-2\/2026\/01\/studio_square_thumbnail.jpg","eyebrow":"","headline":"FROM THE CULTURE","dek":"FROM THE CULTURE is a podcast that explores the inner workings of organizational culture that enable companies to thrive, teams to win, and brands to succeed. If culture eats strategy for breakfast, then this is the most important conversation in business that you arent having.","subhed":"","description":"","ctaText":"Listen","ctaUrl":"https:\/\/www.youtube.com\/playlist?list=PLvojPSJ6Iy0T4VojdtGsZ8Q4eAJ6mzr2h","theme":{"bg":"#2b2d30","text":"#ffffff","eyebrow":"#9aa2aa","subhed":"#ffffff","buttonBg":"#3b3f46","buttonHoverBg":"#3b3f46","buttonText":"#ffffff"},"imageDesktopId":91470870,"imageMobileId":91470866,"shareable":false,"slug":""}} Purpose, mission, conviction For instance, intuitively we know that people are more engaged when they feel connected to something with greater meaning, call it purpose or mission. I like to think of it as conviction. Regardless of the nomenclature, this meaning gives the organization a strategic North Star to guide its way and a reason for being that people can buy into, giving their labor more meaning. However, many businesses rely on external incentives, like the carrot and stick of promotions, and superficial metrics like stock prices and productivity as the primary drivers of work motivation. But people want more from their organizations than the transactional exchange of labor for wagesa transaction that, in itself, seems unbalanced these days on account of burnout and quiet-cracking. No wonder workers in the United States are increasingly declining promotions on the job; “moving up the ladder” is no longer seen as the ultimate reward of work. People want to belong. They want to feel safe. They want to feel appreciated. They want their labor to matter. This is all basic stuff, right? Its obvious, and that’s the problem. The obvious nature of “the basics” can cause leaders to inadvertently ignore them. In doing so, they subsequently foster environments where people feel disconnected and detached from their work. And no one wants that. Back to basics So, what are we to do? Our conversation with Nadia Kokni, vice president of global brand marketing at Puma, for the latest episode of our podcast, From the Culture, provides a clear recommendation: Get back to the basics. Get back to the obvious stuff that isn’t so obvious until someone points it out to you. That is to say, we have to remind ourselves of all the things we inherently know but have forgotten along the way amid the onslaught of information life presents us with on a day-to-day basis. When the foundation begins to break down, so goes everything else. Take music acts, for instance. When a band loses its way after a successful run of album releases, what do they do to rekindle their good fortune? They go back to basics. They reunite with the producers and songwriters from the first album. They go back to the studio where they first recorded. They try to summon the spirit that got them into music in the first place. They hearken back to all those things that got them where they arethe foundational things they likely took for granted on the road to their ascension. Now that I’ve gotten back in the water as a fortysomething-year-old, attempting to stick to a New Year’s resolution to live a healthier life, I’ve found myself thinking a lot about Ivy’s practices. During my morning workouts, I’m much more conscious of my stroke technique and foot placement while kicking, making adjustments here and there to be better. Despite all my years of swimming, I’m still working on the basicsand the same goes for how we think about our work. When things get off course, you have to go back to basics. If we aim to improve how our organizations function, perhaps we should start with the deceptively simple things that we know but often forget. I know it’s obvious, but the obvious typically isn’t obvious until someone points it out to you. And that’s the point. {"blockType":"mv-promo-block","data":{"imageDesktopUrl":"https:\/\/images.fastcompany.com\/image\/upload\/f_webp,q_auto,c_fit\/wp-cms-2\/2026\/01\/studio_16-9.jpg","imageMobileUrl":"https:\/\/images.fastcompany.com\/image\/upload\/f_webp,q_auto,c_fit\/wp-cms-2\/2026\/01\/studio_square_thumbnail.jpg","eyebrow":"","headline":"FROM THE CULTURE","dek":"FROM THE CULTURE is a podcast that explores the inner workings of organizational culture that enable companies to thrive, teams to win, and brands to succeed. If culture eats strategy for breakfast, then this is the most important conversation in business that you arent having.","subhed":"","description":"","ctaText":"Listen","ctaUrl":"https:\/\/www.youtube.com\/playlist?list=PLvojPSJ6Iy0T4VojdtGsZ8Q4eAJ6mzr2h","theme":{"bg":"#2b2d30","text":"#ffffff","eyebrow":"#9aa2aa","subhed":"#ffffff","buttonBg":"#3b3f46","buttonHoverBg":"#3b3f46","buttonText":"#ffffff"},"imageDesktopId":91470870,"imageMobileId":91470866,"shareable":false,"slug":""}}
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For more than 60 years, contraception has been almost exclusively a womens responsibility. Today, women have more than 14 modern contraceptive options, while men have just two: condoms and vasectomies. That imbalance has pushed women to shoulder physical side effects, financial burden, medical risks, and the career impact of family planningcosts that have been accepted as the status quo for far too long. But the tide is shifting. Men are increasingly vocal about wanting to participate in family planning, and new science is finally catching up. For the first time in history, there are multiple male contraceptives in clinical trials, some only a few years away from approval. For companies and investors, this isnt just a public health opportunity, its a multibillion-dollar business opportunity in modern healthcare. A $25 Billion Opportunity The numbers are staggering. In the U.S. alone, there are approximately 70 million sexually active men ages 19 to 60. A landmark survey of 6,313 men in the U.S. found that 82% would try a new male contraceptive at some point in their lives. The same survey found that 49% of men would try a new male contraceptive within 12 months of it being on the market. A downside case looks like 34.3 million potential male contraceptive users. Some estimate that there are 17 million early adopters.Reaching just a fraction of the men interested in male contraception would result in a blockbuster product: For example, 5 million prescriptions for male contraception in the U.S. annually (half of the number of women who are on the Pill) would result in $10 billion-plus of annual recurring revenue. Globally, the opportunity is even larger. There are roughly 2.5 billion sexually active men in the world, and surveys indicate that interest in male contraceptives is even higher in countries like the U.K., Europe, Canada, and Australia. This market potential is why Amboy St. Ventures highlighted male contraception as one of the largest ghost markets in womens health.Sexual health is routinely underestimated by investors, yet the category routinely proves its commercial strength time and time again. Viagra and Cialis each scaled to blockbuster status with annual revenues of $1.8 billion and $2.5 billion for Pfizer and Eli Lilly, respectively. Truvada for HIV preexposure prophylaxis generated approximately $3 billion for Gilead in 2018 by enabling safer sexual activity. Meanwhile, testosterone and hormone-replacement therapies represent another multibillion-dollar sector, driven largely in part by the desire to preserve libido and sexual well-being. Theres no reason male contraception cant become the next big sexual health blockbuster. A Digital-First Model We are in the age of telemedicine. Hims & Hers (valued at $8.7 billion today) launched by targeting mens health needs, such as erectile dysfunction, premature ejaculation, and hair loss. It proved what many underestimated: Men will seek out healthcare when it is accessible, discreet, and convenient. The early adopters who want male contraceptives are similarly digitally native. They wont need their doctor to recommend a new contraceptive; theyll be actively searching for it on their phones. On a recent episode of the podcast Cheeky Pint, Dave Ricks, the CEO of Eli Lilly, said that the reason why LillyDirect works so well for GLP-1s is because The diagnosis step [is] dead easy. Everybody knows the biomarker tool in their bathroom. It’s called the scale. They can know if the drug’s working, and we can offer telehealth post-pandemic at scale. In other words, a straightforward condition and clear feedback loop make remote care feasible. Male contraception fits that mold perfectly: No complex diagnosis or workup is neededa simple at-home sperm check can provide confidence that the method is working. Furthermore, the need for contraception is even more universal than reducing obesity and presents a massive opportunity for a first mover to capture the male birth control market via a direct-to-consumer, digital-first approach. Whats in Development After decades of little progress, several novel male contraceptives are now in clinical trials, addressing a range of preferences: NES/T (Nesterone-Testosterone gel): The most clinically advanced product, NES/T is a topical gel applied to the shoulders daily. Inspired by products in the TRT and HRT space, NES/T delivers a combination of hormones to suppress sperm production while maintaining normal hormone levels and minimizing side effects. A Phase II b trial including 462 couples was recently completed to evaluate its safety, efficacy, and reversibility. Contraline, which secured the development rights from the Population Council, is now preparing for a Phase III trialthe first Phase III male contraceptive trial in history. YCT-529: The nonhormonal daily pill temporarily halts sperm production by blocking a vitamin A pathway in the testes. The first human safety study showed promising tolerability, and now YourChoice Therapeutics is testing whether it reliably suppresses sperm in a Phase I b/II a trial. This compound could become a convenient oral contraceptive for men if it proves safe, effective, and reversible. ADAM: This is a long-acting, reversible contraceptive implant (essentially an IUD for men). ADAM is a nonhormonal hydrogel implanted into the vas deferens, blocking sperm passage until the gel dissolves or is removed. A first-in-human trial showed ADAM is safe and effective for two years. Contraline, the company behind ADAM, is advancing the device toward a larger trial. Given the potential $25 billion-plus market size and mens desire for having multiple options to choose from (just like women do), it is unlikely that male contraception will be a winner-takes-all market. Each of these products may be a blockbuster in its own right. In 1960, the launch of the female Pill sparked a social revolution and created one of the most profitable drug categories in history. Sixty-plus years later, the next sexual health revolution is overdue. This time, it may be led by men. (Disclosure: Foreground Capital is an investor in Contraline and YourChoice Therapeutics, and Amboy St. Ventures is an investor in Contraline.)
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E-Commerce
While speaking at the World Economic Forum in Davos, Switzerland, on January 21, Jamie Dimon, chairman and CEO of JPMorgan Chase, said AI could bring about “civil unrest” by destroying jobs, and that businesses and governments need to step in to help. He made the comments in response to a question about whether AI will lead to fewer jobs over the next several years. Dimon said he believes the impact won’t be as catastrophic to the labor market as some are predicting, but he also didn’t deny some inevitable upheaval. “Don’t put your head in the sand,” he urged. “It is what it is. We’re gonna deploy it.” He continued, “Will it eliminate jobs? Yes. Will it change jobs? Yes. Will it add some jobs? Probably. . . . However, it may go too fast for society, and if it goes too fast for society thats where governments and businesses [need to] in a collaborative way step in together and come up with a way to retrain people and move it over time. Dimon pitched the idea that local governments and businesses are going to need to provide support to workers in the form of income assistance programs, relocation assistance, and retraining to avoid mass unemployment. “We’re not gonna kill all of our employees because of AI,” he said. “We’re just not.” The CEO also said that phasing in the technology slowly is the best approach in order to give people time to adjust and for businesses to come up with solutions, even if that means additional government regulation. He cautioned that companies should not conduct mass layoffs all at once: Youll have civil unrest. You want the government to tell you you cant lay off a whole bunch of people at JPMorgan? moderator Zanny Minton Beddoes, editor-in-chief of The Economist, asked. Wed agree, Dimon replied. If we have to do that to save society. He caveated this should be done at a local levelfor example, governments providing incentives for retraining employees or giving them assistance. In the past, Dimon hasn’t been shy about criticizing the government for too much regulation or what he deems the wrong regulation. In fact, he opposes other precautionary measures like capping credit card interest at 10%. Last year, he called the government “inefficient” and “not very competent” and said he hoped the Department of Government Efficiency would be “quite successful.” Regardless of the worries that Dimon expressed about the pace of AI, job losses, and the potential for the technology to “do something terrible,” he seemed ready to accept his own company’s fatewhatever it may be. When asked if JPMorgan will have fewer employees over the next five years, he predicted that it would. Still, not everyone agreed with Dimon’s statements on AI’s impact on jobs. Jensen Huang, chief executive of Nvidia, said that labor shortages are the issue we should be more concerned with, arguing that AI is actually creating more roles than it is stealing. “This is the largest infrastructure build-out in human history,” Huang said. “That’s gonna create a lot of jobs.”
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